DHA: One of the major building blocks of the brain, the omega-3 fatty acid docosahexaenoic acid (DHA) is critical for optimal brain health and function at all ages of life. Researchers are now finding that DHA provides brain-boosting benefits in infants and aging adults. A key mechanism of DHA is the protection of neural tissue by the production of Resolvin and Protectin D.
Tocopherol: Also known as Vitamin E (alpha, delta, and gamma) which has been found to reduce the production of inflammation by downregulating the production of the transcriptional factor NFkB responsible for signaling DNA to manufacture the inflammatory chemical.
Ascorbic Palmitate: Unique to the different formulations of Vitamin C is this fat-soluble form which can easily enter into the blood supply feeding the brain. Once in the brain, Vitamin C is a major antiinflammatory and free radical scavenger reducing inflammation.
Quercetin: This is a natural polyphenolic, flavonoid antioxidant and has a number of important effects on the metabolism of the brain and reduction of inflammation. First, Quercetin can increase the production of mitochondria starting within 7 days yielding a higher production of energy as ATP (adenosine triphosphate). This ATP is used to run cellular functions which can be perceived as clearing thoughts, more energy and loss of fogginess. Second, Quercetin downregulates the production of the transcriptional trigger for inflammation, the notorious NFk.
Glutathione: Glutathione functions as the front-line defense against oxidative stress in the brain. After trauma, the levels of Glutathione are reduced, through consumption and damage to the enzyme system that regenerate it, and this allows for the accumulation of free radicals. This increased Oxidative Stress, which damages neurons and alters the molecular chemistry in the brain.
EGCG: Epigallocatechin gallate is the active agent in Green Tea. Studies on post-stoke patients and those with dementia and Alzheimer’s disease all benefited with an improvement in cognitive functioning when placed on EGCG.
